當(dāng)前位置:自然基因科技有限公司>>離體器官和組織系統(tǒng)>> Graz離體組織浴槽系統(tǒng)
Graz離體組織浴槽系統(tǒng)的簡單介紹
HSE—HA生理學(xué)系統(tǒng)是一系列應(yīng)用廣泛的完備產(chǎn)品,可用于整體動物生理學(xué)、立體或在體器官和組織灌注及組織浴槽研究。這些系統(tǒng)具有廣泛的應(yīng)用,包括傳統(tǒng)的安全藥理學(xué)、DMPK、毒理學(xué)、呼吸系統(tǒng)、心臟病學(xué)、分子生物學(xué)和生理學(xué)。每個系統(tǒng)都設(shè)計了標(biāo)準(zhǔn)的組件,再加一些其他配置以適合特殊研究的需要。。標(biāo)注組慘馕蹲湃綣閌切枰鐘猩璞概淦?,或諊银行系统升级,或者是完整祬蠕套产屏P愣賈恍枰郝蛐枰墓辜?/SPAN>HSE-HA生理學(xué)系統(tǒng)為你提供各種工具,使你的研究走向多產(chǎn)和成功。
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• Designed for vascular rings but suitable for most standard pharmacological experiments
• Permits experiments both on smooth muscle, cardiac (atria), or skeletal muscles preparations
• Clear, 4-channel arrangement
• Rigid construction
• Contractions can be measured isometrically or isotonically
• Interchangeable tissue vessels: 2, 5, 10 or 20 ml
• Experiments with minimum test substance quantities are possible using small tissue vessels
• Adaptable to different tissue preparations by suitable form of tissue supports
• Tissue holders with integral field stimulating electrode available
• Simple to operate, easy to clean
The Graz Organ Bath can be used for many standard pharmacological experiments. This apparatus was developed for experiments on small isolated vascular rings (1 to 2 mm dia.) with special attention to a low incubation volume of the medium. The smallest tissue vessel available has a volume of 2 ml. The muscle contractions produced in these experiments can be measured either as forces (isometrically) or as displacements (isotonically).
The organ bath is also available in variable versions. Larger tissue vessels of 5, 10 or 20 ml are available for larger vessels and other muscle preparations. These baths can also be used for experiments on papillary muscle or isolated atria (e.g. guinea-pig), with provision for electrical stimulation. The F-30 isometric transducer that we recommend (See page I4) can easily be replaced by different transducers without any modification of the apparatus.
The main consideration in designing the bath has been a simple and clear arrangement, without neglecting the necessary stability. A rigid construction is an essential requirement for measuring small contraction forces. A rigid Plexiglas baseplate carriers 4 vertical rods on which the individual components are mounted. Tissue vessels and suitable holders are available in 4 different sizes. The perfusion solution is aerated by glass frits fused into the vessel bottom. A needle valves is provided for each tissue vessel to permit accurate adjustment of the gas flow.
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