肌動蛋白結(jié)合蛋白LIM蛋白3抗體（）
英文名稱：  Anti-ABLIM3 
濃度： 1mg/1ml 
抗體來源： Rabbit

克隆類型：polyclonal 

交叉反應(yīng)： Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, 

產(chǎn)品類型: 一抗  

性    狀: Lyophilized or Liquid
保存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

產(chǎn)品介紹 ：The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS （striated muscle activator of Rho signaling） dependent activation of serum-response factor （SRF）, thereby modulating transcription.