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產(chǎn)地：荷蘭

動物步態(tài)分析系統(tǒng)Catwalk XT是什么
是一個定量分析嚙齒類動物模型腳步和步態(tài)的完整系統(tǒng)。
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為什么要使用動物步態(tài)分析系統(tǒng)
    封閉的走道可以方便的評估非受迫動物移動的腳印及步態(tài)，獲得自然步態(tài)。
    Illuminated Footprints™技術(shù)捕獲真實動態(tài)的腳印。
    Illuminated Footprints™技術(shù)可以實現(xiàn)身體重量分配測量。

動物步態(tài)分析系統(tǒng)是如何工作的
    CatWalk XT動物步態(tài)分析系統(tǒng)是一個包含軟硬件的完整系統(tǒng)。它使用Illuminated Footprints™技術(shù)，捕獲每一個腳步的細節(jié)。通過自動腳印分類節(jié)省您大量的實驗時間。
    動物步態(tài)分析系統(tǒng)的核心設(shè)備是一個封閉的步行臺，老鼠可以從一端走到另一端。腳印照明技術(shù)實現(xiàn)了利用高速攝像機從步行臺下方捕獲真正的腳印。
    腳印照明技術(shù)甚至可以探測壓力差異，從而測量動物體重在四腳的分配情況。
    為了動物保持自然步態(tài)沒有采取強制措施。在步態(tài)分析中行走速度是一個非常重要的因素。步態(tài)分析系統(tǒng)可以測定行走速度，進行數(shù)據(jù)選擇和分析。不需要外部標(biāo)記，修剪指甲，大量光照等。
    測量的參數(shù)包括，著地時間，懸空時間，步長，壓力，左右腳間距，前后腳印記間距，步序等。

誰適合使用動物步態(tài)分析系統(tǒng)
以下研究領(lǐng)域可以使用動物步態(tài)分析系統(tǒng)CatWalk XT進行損傷，恢復(fù)，藥物干預(yù)等方面的評估。

神經(jīng)損傷	神經(jīng)退行性變	神經(jīng)疾病	疼痛癥狀
脊髓損傷	神經(jīng)性疼痛	關(guān)節(jié)炎	中風(fēng)
帕金森癥	運動失調(diào)	創(chuàng)傷性腦損傷（TBI）	末梢神經(jīng)損傷

版的動物步態(tài)分析系統(tǒng)CatWalk XT9.0新增功能
版的動物步態(tài)分析系統(tǒng)9.0增加了交互式腳印測量技術(shù)，這使該系統(tǒng)在自動腳印分析方面前進了一大步。交互式腳步測量功能是一個全新擴展模塊，用來測量動物趾端開口距和腳爪朝向。此外，動物每次穿越步行臺時，新的數(shù)據(jù)分段技術(shù)都能幫助您獲取更高質(zhì)量的數(shù)據(jù)。

交互式腳印測量功能
    新的交互式腳印測量擴展模塊可以測量下列參數(shù)：
•           遠趾端開口距
•           近趾端開口距
•           腳印長度
•           腳爪朝向
    趾端開口距和腳印長度用來計算坐骨神經(jīng)功能指數(shù)。該指數(shù)用于評估鼠類的坐骨神經(jīng)功能恢復(fù)情況。

數(shù)據(jù)分段概要功能
    動物步態(tài)分析系統(tǒng)9.0提供了數(shù)據(jù)分段概要功能，允許您根據(jù)速度參數(shù)和連續(xù)步行的次數(shù)選擇動物步行片段，從而提高您的試驗數(shù)據(jù)質(zhì)量并允許您控制動物運動速度。

新增統(tǒng)計參數(shù)
    在動物步態(tài)分析系統(tǒng)9.0中除了新增的腳印測量參數(shù)，用來計算坐骨神經(jīng)功能指數(shù)。另外，新的參數(shù)還有：單足支撐時間，起始雙足支撐時間，末尾雙足支撐時間。這些參數(shù)用于研究疼痛實驗中動物的單只和雙只后腿支撐所用時間。

足印自動分類功能
    動物步態(tài)分析系統(tǒng)包括了足印自動分類功能。只需按動按鈕，系統(tǒng)將自動分類動物步行過程中的足印。如果系統(tǒng)提示不能分類的足印，系統(tǒng)會自動突出這些足印方便您手動標(biāo)記。前期測試結(jié)果令人印象深刻：在足印分類中節(jié)省了高達70%的時間，從而使整個實驗的時間也節(jié)約了50%。的物有所值！
   “在各種不同的動物模型中，足印自動分類技術(shù)都表現(xiàn)的很出色。腳爪探測非常可靠，大多數(shù)的探測失誤的爪印都是由于步行臺上的污跡?？梢愿鶕?jù)足印和時間視圖能夠很容易識別有錯誤的片段，從而使您手動修改。超過90%的腳印分類都不需要改正。對于實驗人員來說足印分類也成了一項有趣的工作” 法國賽諾菲安萬特制藥集團(Sanofi-Aventis)的Frankfurt博士這樣評價道。

技術(shù)參數(shù)：

Product code	ZCWP-8001
Walkway dimensions (LxWxH)	130 x 68 x 152 cm (51” x 27” x 60”)
Walkway light	535nm green LED array and 625nm red LED array
Camera frame rate	100 fps
Camera CCD imager	1/2” VGA
Camera S/N Ratio	>58 dB
Combined power supply	24VDC with 3 exchangeable plug adapters
Computer processor	2.5 GHz dual core, internal memory: 4 GB
Computer minimum hard disk space	100 GB
Computer minimum screen resolution	1280 x 1024 pixels
Computer OS	Windows XP 32-bit Professional with SP 3 or Windows Vista Business 32-bit with SP 1
Software data output	Excel 2003 (.xls) or Excel 2007 (.xml)

參考文獻
The CatWalk gait analysis in assessment of both dynamic and static gait changes after adult rat sciatic nerve resection
R Deumens, RJP Jaken, MAE Marcus, EAJ … - Journal of neuroscience …, 2007 - Elsevier
Functional repair of neurotmesis has been proven most challenging in regenerative
medicine. Progress in this field has shown that functional repair not only requires axon
regeneration, but also selectivity in target reinnervation. Although selectivity in target ...

CatWalk gait analysis in assessment of functional recovery after sciatic nerve injury
A Bozkurt, R Deumens, J Scheffel, DM O'Dey, J … - Journal of neuroscience …, 2008 - Elsevier
Following peripheral nerve injury repair, improved behavioural outcome may be the most important
evidence of functionality of axon regeneration after any repair strategy. A range of behavioural
testing paradigms have been developed for peripheral nerve injury research. Complete ...

Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries
FPT Hamers, AJ Lankhorst, TJ van Laar, WB … - Journal of …, 2001 -
... During a first automatic pass the bright areas in the individual frames are labeled and
in- dexed; in the subsequent pass, these spots are interactively CATWALK GAIT
ANALYSIS 189 Page 4. ... Page 5. CATWALK GAIT ANALYSIS 191 FIG. ...

CatWalk'automated quantitative gait analysis as a novel method to assess mechanical allodynia in the rat; a comparison with von Frey testing
DH Vrinten, FFT Hamers - Pain, 2003 - Elsevier
A characteristic symptom of neuropathic pain is mechanical allodynia. In animal models of neuropathic
pain, mechanical allodynia is often assessed using von Frey filaments. Although the forces applied
with these filaments are highly reproducible, there are various disadvantages of using this ...

CatWalk-assisted gait analysis in the assessment of spinal cord injury
FPT Hamers, GC Koopmans, EAJ … - Journal of …, 2006 -
Gait analysis plays an important role in the assessment of neurological function in many disease
models. In this review, we focus on the newly developed CatWalk system for gait analysis. CatWalk
was originally developed as a tool to enhance assessment of functional outcome in spinal ...

The CatWalk method: Assessment of mechanical allodynia in experimental chronic pain
AF Gabriel, MAE Marcus, GHIM Walenkamp, … - Behavioural brain …, 2009 - Elsevier
... Available online 25 December 2008. Abstract. The CatWalk gait analysis system has recently
been suggested as a rapid and objective alternative method over the von Frey test to assess
mechanical allodynia in chronic neuropathic pain models. ...

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